Letter: Kinetic classifications of Antitumour Drugs.

Tin-based Antitumour Drugs

We have been active in the synthesis and characterization of tin-based antitumour compounds for several years and we would like to summarize here the results that have already been patented(1) and that may therefore be disclosed(2). We synthesized some diorganotin 2,6-pyridinedicarboxylates.The dimethyltin compound has been found inactive in vitro, whereas the di-n-butyltin, di-t-butyltin and d...

Tin-Based Antitumour Drugs: New Developments

An overview of the in vitro test results on several human tumour cell lines of several series of organotin compounds synthesized at the Free University of Brussels VUB. Several compounds exhibit excellent antitumour activities. in vivo screening also gave very promising results.

The medical letter on drugs and therapeutics.

Electrochemical Synthesis and Kinetic Evaluation of Electrooxidation of Acetaminophen in the Presence of Antidepressant Drugs

With the aim of obtaining information about drug-drug interaction (DDI) between acetaminophen and some of antidepressant drugs (fluoxetine, sertraline and nortriptyline), in the present work we studied the electrochemical oxidation of acetaminophen (paracetamol) in the presence of these drugs by means of cyclic voltammetry and Controlled-potential coulometry. The reaction between N-acetyl-p-ben...

Electrochemical Synthesis and Kinetic Evaluation of Electrooxidation of Acetaminophen in the Presence of Antidepressant Drugs

With the aim of obtaining information about drug-drug interaction (DDI) between acetaminophen and some of antidepressant drugs (fluoxetine, sertraline and nortriptyline), in the present work we studied the electrochemical oxidation of acetaminophen (paracetamol) in the presence of these drugs by means of cyclic voltammetry and Controlled-potential coulometry. The reaction between N-acetyl-p-ben...